Immigration
Republicans will try to block implementation of Obama's new immigration policies, which would give a three-year reprieve from the threat of deportation to parents of children with legal status.
Health care
By the end of June, the U.S. Supreme Court is expected to decide a case that challenges whether the Affordable Care Act's subsidies are allowed in states without their own insurance exchanges.
Taxes
More than 50 expired tax breaks won renewal in December, but only for tax year 2014. Congress will debate another extension and weigh an overhaul of the tax code for the first time since 1986.
Roads
The Highway Trust Fund could be broke by the end of May. Will Congress consider the first federal gas tax increase since 1993? There is some bipartisan support for the idea as gas prices continue to fall.